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Protein Domain : Translational activator Gcn1

Primary Identifier  IPR033173 Type  Family
Short Name  Gcn1
description  Gcn1 acts as a translation activator that mediates translational control by regulating Gcn2 kinase activity. The eIF2alpha kinase Gcn2 is activated under stress conditions by a mechanism involving Gcn2 binding to activator protein Gcn1 [, ]. Phosphorylation of eIF2alpha results in general protein synthesis repression and increased translation of specific mRNAs. Protein ILITYHIA from Arabidopsis is involved in immunity against bacterial infection and in non-host resistance []and is required for the bacterium-triggered stomatal closure response [].

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9 Protein Domain Regions