Primary Identifier | MGI:3646919 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 668225 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable microtubule severing ATPase activity. Involved in microtubule severing; negative regulation of axon regeneration; and negative regulation of wound healing, spreading of epidermal cells. Predicted to be located in cell leading edge. Orthologous to human FIGNL2 (fidgetin like 2). PHENOTYPE: Conditional knock-out in cultured adult dorsal root ganglion neurons results in longer axons and attenuated growth cone retraction in response to inhibitory molecules. [provided by MGI curators] |