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Protein Domain : Translocon-associated protein (TRAP), alpha subunit

Primary Identifier  IPR005595 Type  Family
Short Name  TRAP_alpha
description  The alpha-subunit of the TRAP (translocon-associated protein) complex is a single-spanning membrane protein of the endoplasmic reticulum (ER) []. The four-subunit (alpha, beta, gamma and delta) TRAP complex localises in the ER membrane and associates with the Sec61 translocon as a heterotetramer []. It also interacts with palmitoylated calnexin (CALX), the interaction is required for efficient folding of glycosylated proteins []. TRAP complex may also be involved in endoplasmic reticulum-associated degradation [].

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7 Protein Domain Regions