Primary Identifier | IPR005595 | Type | Family |
Short Name | TRAP_alpha |
description | The alpha-subunit of the TRAP (translocon-associated protein) complex is a single-spanning membrane protein of the endoplasmic reticulum (ER) []. The four-subunit (alpha, beta, gamma and delta) TRAP complex localises in the ER membrane and associates with the Sec61 translocon as a heterotetramer []. It also interacts with palmitoylated calnexin (CALX), the interaction is required for efficient folding of glycosylated proteins []. TRAP complex may also be involved in endoplasmic reticulum-associated degradation []. |