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Allele : b2b2736.2Clo Mutant line 2736.2; Bench to Bassinet Program (B2B/CVDC), mutation 2736.2 Cecilia Lo
Primary Identifier  MGI:5560812 Allele Type  Chemically induced (ENU)
Gene  b2b2736.2Clo Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  B2B/CvDC
description  Summative Diagnosis:

Mutant Type 2:
Cardiovascular Phenotype: Persistent truncus arteriosus (PTA, Type 1), atrioventricular ventricular septal defect (AVSD), right aortic arch (RAA), and aberrant left subclavian artery forming vascular ring
Noncardiovascular Phenotype: growth retardation, microphthalmia, syndactyly, micrognathia, cleft palate, hypoplastic kidneys, lungs, and thymus

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID Code Description
1100 Atrioventricular canal (endocardial cushion defect)
2700 Abnormal aortic arch
2760 Vascular ring
4906 Non-cardiac abnormality
0510 Truncus arteriosus type i
2720 Right aortic arch
2730 Aberrant left subclavian artery
4170 Hand and/or foot anomaly
4174 Syndactyly

molecularNote  This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. It is a subline of b2b2736Clo.
  • mutations:
  • Undefined
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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