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Protein Coding Gene : Angptl4 angiopoietin-like 4

Primary Identifier  MGI:1888999 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  57875
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables enzyme inhibitor activity. Involved in negative regulation of apoptotic process and triglyceride homeostasis. Acts upstream of or within negative regulation of endothelial cell apoptotic process. Located in extracellular space. Is expressed in several structures, including brain; genitourinary system; heart; hemolymphoid system gland; and integumental system. Orthologous to human ANGPTL4 (angiopoietin like 4).
PHENOTYPE: Mice homozygous for disruptions in this gene display decreased levels of triglycerides and cholesterol and a lower increase in body fat after exposure to gut microbiota. [provided by MGI curators]
  • synonyms:
  • Angptl4,
  • FIAF,
  • HFARP,
  • NG27,
  • BK89,
  • angiopoietin-like 4

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For