| Primary Identifier | MGI:96446 | Organism | mouse, laboratory |
| Chromosome | 12 | Mgi Type | gene segment |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables antigen binding activity and immunoglobulin receptor binding activity. Involved in B cell differentiation. Acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity; phagocytosis; and positive regulation of immune response. Located in external side of plasma membrane and extracellular space. Part of immunoglobulin complex, circulating. Is active in cytoplasm. Orthologous to several human genes including IGHG1 (immunoglobulin heavy constant gamma 1 (G1m marker)); IGHG2 (immunoglobulin heavy constant gamma 2 (G2m marker)); and IGHG3 (immunoglobulin heavy constant gamma 3 (G3m marker)). PHENOTYPE: Mutant mice are viable and fertile but show impaired primary and secondary Igh-4 immune responses. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
