Primary Identifier | MGI:2686058 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 382913 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables microtubule binding activity. Predicted to be involved in base-excision repair. Predicted to act upstream of or within DNA repair. Located in cytoplasm and mitotic spindle. Is expressed in primordial germ cell of gonad. Orthologous to human NEIL2 (nei like DNA glycosylase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased age-related DNA damage, loss of telomeres and increased induced lung inflammation. [provided by MGI curators] |