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Protein Coding Gene : Myo1c myosin IC

Primary Identifier  MGI:106612 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  17913
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables microfilament motor activity. Acts upstream of or within several processes, including cellular response to type II interferon; positive regulation of protein targeting to membrane; and vesicle transport along actin filament. Located in several cellular components, including brush border; cytoplasmic vesicle; and stereocilium. Is expressed in cochlea. Orthologous to human MYO1C (myosin IC).
PHENOTYPE: Mice homozygous for a knock-in (Y61G) mutation that sensitizes to N6-modified ADP analogs display altered fast adaption in vestibular hair cells. Mice homozygous for a nuclear isoform-specifc knock-out allele exhibit minor changes in bone marrow density and red blood cells. [provided by MGI curators]
  • synonyms:
  • mm1beta,
  • myosin-Ibeta,
  • MGD-MRK-35069,
  • myr2,
  • MGI:2144662,
  • Myo1c,
  • expressed sequence C80397,
  • C80397,
  • myosin IC

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For