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Protein Coding Gene : Prdx6 peroxiredoxin 6

Primary Identifier  MGI:894320 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  11758
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables 1-acylglycerophosphocholine O-acyltransferase activity; peroxidase activity; and phospholipase A2 activity. Acts upstream of or within bleb assembly and response to reactive oxygen species. Located in cytosol. Is expressed in several structures, including alimentary system; central nervous system; liver and biliary system; respiratory system; and sensory organ. Orthologous to human PRDX6 (peroxiredoxin 6).
PHENOTYPE: Mice homozygous for disruptions of this gene show no macroscopic or microscopic abnormalities. However, they have an increased susceptibility to oxidative stress. [provided by MGI curators]
  • synonyms:
  • Ltw4,
  • GPx,
  • aiPLA2,
  • MGI:3035058,
  • Prdx6,
  • MGD-MRK-11944,
  • expressed sequence AA690119,
  • RIKEN cDNA 9430088D19 gene,
  • AA690119,
  • CC26,
  • MGI:2444784,
  • 9430088D19Rik,
  • liver 20-30 thousand M.Wt. protein 4,
  • NSGP,
  • Aop2,
  • acidic calcium-independent phospholipase A2,
  • CP-3,
  • 1-cysPrx,
  • MGI:96849,
  • MGD-MRK-11926,
  • Ltw-4,
  • MGD-MRK-1637,
  • MGD-MRK-11921,
  • Lvtw-4,
  • brain protein 12,
  • liver 20-30 thousand M.Wt protein 4,
  • 1-Cys Prx,
  • Brp-12,
  • peroxiredoxin 6

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For