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Publication : Identification and characterization of a calcium-binding protein in the mouse chorioallantoic placenta.

First Author  Tuan RS Year  1986
Journal  Biochem J Volume  233
Issue  1 Pages  41-9
PubMed ID  3513762 Mgi Jnum  J:49094
Mgi Id  MGI:1276664 Doi  10.1042/bj2330041
Citation  Tuan RS, et al. (1986) Identification and characterization of a calcium-binding protein in the mouse chorioallantoic placenta. Biochem J 233(1):41-9
abstractText  Mouse chorioallantoic placenta contains a specific calcium-binding protein (MCaBP). A procedure involving gel filtration and ion-exchange chromatography was developed to purify the MCaBP. The MCaBP activity increased as a function of embryonic gestation and was highly specific for Ca2+. The MCaBP is a monomeric protein of Mr 57000, with pI 4.7. Specific antibodies were prepared against the MCaBP and were used to localize the MCaBP to syncytiotrophoblasts of the chorionic villi of mouse chorioallantoic placenta. These properties suggest that the MCaBP may be involved in transplacental calcium transport.
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