| Primary Identifier | MGI:1201402 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 12776 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables C-C chemokine receptor activity. Acts upstream of or within chemotaxis. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system; retina; and thymus primordium. Orthologous to human CCR8 (C-C motif chemokine receptor 8). PHENOTYPE: Mice homozygous for either of two independently generated knock-out alleles show normal lung eosinophilia and Th2 cytokine responses in OVA-elicited asthma models. Mice homozygous for a third knock-out allele show a delay in onset of clinical signs of experimental autoimmune encephalomyelitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
