First Author | Anniko M | Year | 1982 |
Journal | Hear Res | Volume | 6 |
Issue | 3 | Pages | 247-58 |
PubMed ID | 6979536 | Mgi Jnum | J:6781 |
Mgi Id | MGI:55253 | Doi | 10.1016/0378-5955(82)90058-2 |
Citation | Anniko M (1982) Specific pathology of the stria vascularis in postnatal progressive genetic inner ear disorder. Hear Res 6(3):247-58 |
abstractText | After reaching normal morphological maturation the stria vascularis of the Shaker-2 (Sh-2) mouse postnatally underwent a progressive degeneration, especially of the intermediate cell layer. Considerable changes were present on the 3rd week after birth. The marginal cells became atrophic and showed a reduction in the number and extent of the cellular extensions towards the intermediate cell layer. The intermediate cells disintegrated but were present 9 weeks after birth. The basal cells showed a normal morphology. Specific inclusion bodies were identified in the marginal cells from the 3rd week on. Occasionally such inclusions occurred in marginal cells. In the Shaker-1 (Sh-1) a flattening of intermediate cells occurred but otherwise no pathological changes were found 6--9 weeks after birth. |