Primary Identifier | MGI:1341894 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 20448 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. Predicted to be involved in ganglioside biosynthetic process and oligosaccharide metabolic process. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in Golgi apparatus and membrane. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system; integumental system; and sensory organ. Orthologous to human ST6GALNAC4 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4). PHENOTYPE: Mice homozygous for a null allele exhibit no abnormal phenotype. Double homozygotes lacking St6galnac3 and St6galnac4 exhibit lymph node hemorrhage associated with structural disruption of high endothelial venule. [provided by MGI curators] |