| Primary Identifier | MGI:1194884 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 14026 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables SH3 domain binding activity and profilin binding activity. Involved in actin polymerization or depolymerization and positive regulation of actin filament polymerization. Acts upstream of or within cellular response to type II interferon. Located in focal adhesion; lamellipodium; and phagocytic vesicle. Is expressed in several structures, including central nervous system; genitourinary system; immune system; liver; and retina. Orthologous to human EVL (Enah/Vasp-like). PHENOTYPE: Mice homozygous for a knock-out allele are viable with no apparent defects in gross morphology or histology. Mice homozygous for a different knock-out allele are viable and fertile but display defects in monocyte migration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
