Primary Identifier | IPR040190 | Type | Family |
Short Name | MURQ/GCKR |
description | N-acetylmuramic acid 6-phosphate etherase (MurQ) is an enzyme involved in peptidoglycan recycling in Escherichia coli. In cyanobacteria MurQ may promote low-light adaptation through peptidoglycan recycling []. MurQ contains a sugar isomerase (SIS) domain with similarity to the glucokinase regulatory protein (GKRP) in humans [].GCKR regulates glucokinase (GK), an enzyme responsible for regulating the uptake and storage of dietary glucose []. In the liver, GKRP forms an inhibitory complex with glucokinase (GCK). The disruption and reformation of this complex occurs in response to direct binding of glucose to GCK, and fructose 1-phosphate (F1P) and fructose 6-phosphate (F6P) to GKRP []. |