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Allele : Tg(Alb1-NR1I2)2Rev transgene insertion 2, Ronald M Evans

Primary Identifier  MGI:2386095 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Alb1-NR1I2)2Rev
Strain of Origin  (BALB/c x C57BL/6)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  An activated form of human NR1I2 cDNA fused a mouse liver-specific albumin promoter was used as the transgene. A sequence from the herpes simplex virus VP16 activation domain at the amino terminus of NR1I2 confers activated status to the human protein. Expression of the human transgene was verified by Northern blot analysis of liver tissue from transgenic animals.
  • mutations:
  • Insertion
  • synonyms:
  • Alb-VPSXR,
  • VP-hPXR,
  • Alb-VPSXR,
  • Alb-VP-PXR,
  • VP-hPXR,
  • Alb-VP-PXR
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele