| First Author | Zurawski G | Year | 1994 |
| Journal | Immunol Today | Volume | 15 |
| Issue | 1 | Pages | 19-26 |
| PubMed ID | 7907877 | Mgi Jnum | J:16690 |
| Mgi Id | MGI:64757 | Doi | 10.1016/0167-5699(94)90021-3 |
| Citation | Zurawski G, et al. (1994) Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. Immunol Today 15(1):19-26 |
| abstractText | Interleukin 13 (IL-13) is a recently described protein secreted by activated T cells which is a potent in vitro modulator of human monocyte and B-cell functions. The data, reviewed here by Gerard Zurawski and Jan de Vries, shows that IL-13 shares biological activities with IL-4, their genes are closely linked in both the human and mouse genomes, and there is sequence homology between IL-13 and IL-4 proteins. Although the cloned IL-4 receptor protein (IL-4R) does not bind IL-13, it appears that the functional IL-4R and IL-13R share a common subunit that is important for signal transduction. |
