| First Author | Lee YJ | Year | 2000 |
| Journal | FEBS Lett | Volume | 487 |
| Issue | 2 | Pages | 287-92 |
| PubMed ID | 11150526 | Mgi Jnum | J:67004 |
| Mgi Id | MGI:1929592 | Doi | 10.1016/s0014-5793(00)02367-x |
| Citation | Lee YJ, et al. (2000) An intronless gene encoding a poly(A) polymerase is specifically expressed in testis. FEBS Lett 487(2):287-92 |
| abstractText | Previous work demonstrated that a single pre-mRNA could generate multiple forms of mammalian poly(A) polymerase mRNAs by alternative splicing or alternative polyadenylation. A cDNA encoding a testis-specific poly(A) polymerase was isolated in this study. The transcription level of Papt in testis of a 2 weeks old mouse was much lower than that of the general poly(A) polymerase gene, Pap. However, the transcription ratio of Papt to Pap was reversed in testis of a 4 weeks old mouse. Transient expression analysis showed that GFP-Papt fusion protein is present both in the nucleus and cytoplasm of HeLa cells. These results suggest that Papt is involved in polyadenylation of transcripts expressed during spermatogenesis. |
