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Comment :

Type  MGI:General Description  baclofen treatment fails to induce postsynaptic GABAB receptor mediated hyperpolarization in hippocampal slices treated with bicuculline intertictal bursts are significantly prolonged and an increase in the number of secondary discharges evoked following the primary burst is seen hippocampal slices taken from mice that experienced multiple seizures show a more pronounced ictal discharge pattern of epileptiform activity