Primary Identifier | MGI:6324951 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence, Modified isoform(s) | Gene | Tg(ACTA1-Ppargc1a_ia)BOse |
Strain of Origin | (C57BL/6 x DBA/1)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene contains the following elements: a 2.2 kb DNA fragment containing the promoter, exon 1 and (part of) intron 1 of the human skeletal muscle actin alpha 1 gene, the a isoform cDNA of the mouse peroxisome proliferative activated receptor gamma coactivator 1 alpha gene, and bovine growth hormone poly(A) signal sequences. The a splice variant incorporates alternative 5' exon 1a. Six mouse lines were established and lines B, D, and E were studied. |