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Publication : Treating transcriptional addiction in small cell lung cancer.

First Author  Augert A Year  2014
Journal  Cancer Cell Volume  26
Issue  6 Pages  783-784
PubMed ID  25490443 Mgi Jnum  J:217686
Mgi Id  MGI:5615322 Doi  10.1016/j.ccell.2014.11.012
Citation  Augert A, et al. (2014) Treating transcriptional addiction in small cell lung cancer. Cancer Cell 26(6):783-4
abstractText  Small cell lung cancer (SCLC) is a devastating tumor type with great therapeutic need. In this issue of Cancer Cell, Christensen and colleagues identify THZ1, a CDK7 inhibitor, as a potential therapy for SCLC. Using cells and mouse models, the authors show exquisite sensitivity of SCLC to transcriptional inhibition.
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