| First Author | Chan SO | Year | 1996 |
| Journal | Neurochem Res | Volume | 21 |
| Issue | 4 | Pages | 449-55 |
| PubMed ID | 8734438 | Mgi Jnum | J:51729 |
| Mgi Id | MGI:1326782 | Doi | 10.1007/BF02527709 |
| Citation | Chan SO, et al. (1996) The 66-kDa neurofilament protein (NF-66): sequence analysis and evolution. Neurochem Res 21(4):449-55 |
| abstractText | A 2.5 kb cDNA clone encoding the mouse 66 kd neurofilament protein (NF-66) was isolated and sequenced. The deduced protein sequence contains 501 amino acid residues. Comparison of the mouse, rat and human NF-66 indicated > 90% homology in protein sequence and 85% homology in coding nucleotide sequence. A high degree of homology was observed between NF-66 and other intermediate filament proteins especially in the alpha- helical domain. Zooblot analyses suggested that the putative ancestral gene for vimentin and NF-66 was detectable in the avian. By comparison, the ancestral sequence for GFAP appeared after that for vimentin. |
