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Protein Domain : Repressor of RNA polymerase III transcription Maf1

Primary Identifier  IPR015257 Type  Family
Short Name  Maf1
description  Maf1 is a negative regulator of RNA polymerase III [, ]. It inhibits the de novo assembly of TFIIIB onto DNA []. Maf1 represses Pol III in response to DNA damage, oxidative stress, growth to stationary phase, treatment with rapamycin or chlorpromazine, and blocking of the secretory pathway []. It targets the initiation factor TFIIIB []. Its structure has been solved [].

0 Child Features

0 Parent Features

9 Protein Domain Regions