Primary Identifier | IPR015257 | Type | Family |
Short Name | Maf1 |
description | Maf1 is a negative regulator of RNA polymerase III [, ]. It inhibits the de novo assembly of TFIIIB onto DNA []. Maf1 represses Pol III in response to DNA damage, oxidative stress, growth to stationary phase, treatment with rapamycin or chlorpromazine, and blocking of the secretory pathway []. It targets the initiation factor TFIIIB []. Its structure has been solved []. |