Primary Identifier | MGI:1919451 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 72201 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in cell population proliferation; proteasome assembly; and regulation of translation. Predicted to act upstream of or within proteolysis. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and liver and biliary system. Orthologous to human OTUD6B (OTU deubiquitinase 6B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete perinatal lethality, decreased fetal size, and ventricular septal defects. [provided by MGI curators] |