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Protein Coding Gene : Otud6b OTU domain containing 6B

Primary Identifier  MGI:1919451 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  72201
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in cell population proliferation; proteasome assembly; and regulation of translation. Predicted to act upstream of or within proteolysis. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and liver and biliary system. Orthologous to human OTUD6B (OTU deubiquitinase 6B).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete perinatal lethality, decreased fetal size, and ventricular septal defects. [provided by MGI curators]
  • synonyms:
  • Otud6b,
  • AU015433,
  • 2600013N14Rik,
  • MGI:2140427,
  • OTU domain containing 6B,
  • expressed sequence AU015433,
  • RIKEN cDNA 2600013N14 gene

Features --> Cross References

Genome

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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