| Primary Identifier | MGI:1345162 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 23792 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable metalloendopeptidase activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Is active in glutamatergic synapse and presynaptic membrane. Is expressed in several structures, including alimentary system; exocrine system; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human ADAM23 (ADAM metallopeptidase domain 23). PHENOTYPE: Mice homozygous for an insertional mutation that inactivates the gene are smaller than normal littermates, show delayed lung development, are lethal by postnatal day 14, and display severe tremor and ataxia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
