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Publication : Molecular mechanisms of the PRL phosphatases.

First Author  Rios P Year  2013
Journal  FEBS J Volume  280
Issue  2 Pages  505-24
PubMed ID  22413991 Mgi Jnum  J:209257
Mgi Id  MGI:5566760 Doi  10.1111/j.1742-4658.2012.08565.x
Citation  Rios P, et al. (2013) Molecular mechanisms of the PRL phosphatases. FEBS J 280(2):505-24
abstractText  The phosphatases of regenerating liver (PRLs) are an intriguing family of dual specificity phosphatases due to their oncogenicity. The three members are small, single domain enzymes. We provide an overview of the phosphatases of regenerating liver, compare them to related phosphatases, and review recent reports about each phosphatase. Finally, we discuss similarities and differences between the phosphatases of regenerating liver, focusing on their molecular mechanisms and signalling pathways.
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