Primary Identifier | MGI:2429761 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Slc19a2 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 2 was disrupted by the insertion of a neomycin selection cassette. An aberrantly spliced transcript lacking a 3' portion of exon 2 was identified in homozygous mutant mice by Northern blot analysis. A reduction in high affinity thiamin transport in erythrocytes indicated an absence of functional protein. |