| First Author | Chandley AC | Year | 1987 |
| Journal | Chromosoma | Volume | 95 |
| Issue | 5 | Pages | 345-9 |
| PubMed ID | 3652817 | Mgi Jnum | J:15304 |
| Mgi Id | MGI:63431 | Doi | 10.1007/BF00293181 |
| Citation | Chandley AC, et al. (1987) Cytological evidence that the Sxr fragment of XY,Sxr mice pairs homologously at meiotic prophase with the proximal testis-determining region. Chromosoma 95(5):345-9 |
| abstractText | Self-pairing of the Y chromosome at prophase of meiosis in XY,Sxr male mice appears to take place in many cells to the exclusion of pairing between the Y and the X. This phenomenon offers an explanation for the high level of X-Y separation seen in these males at prophase of meiosis, additional separations being evident, however, when metaphase I (MI) cells are examined. A minority of prophase cells show the Y paired both autologously and with a sub-terminal region of the X which could be the normal pairing region. The balloon-like configurations observed when self-pairing occurs suggest that the distal Sxr fragment is inverted on the Y chromosome of Sxr carrier males in relation to the normal proximal testis-determining (Td)-containing region. |
