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Protein Coding Gene : Arhgap32 Rho GTPase activating protein 32

Primary Identifier  MGI:2450166 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  330914
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable GTPase activator activity. Predicted to be involved in positive regulation of axon extension; positive regulation of neuron migration; and small GTPase-mediated signal transduction. Predicted to act upstream of or within Rho protein signal transduction. Located in actin cytoskeleton; cell cortex; and postsynaptic density. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Used to study autism spectrum disorder. Orthologous to human ARHGAP32 (Rho GTPase activating protein 32).
PHENOTYPE: Mice homozygous for a null mutation are fertile but display abnormal neurite growth. [provided by MGI curators]
  • synonyms:
  • PX-RICS,
  • p200RhoGAP,
  • Rho GTPase activating protein 32,
  • Arhgap32,
  • RIKEN cDNA 3426406O18 gene,
  • Rho GTPase-activating protein,
  • 3426406O18Rik,
  • MGI:1917927,
  • Grit,
  • GC-GAP

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

16 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For