| Primary Identifier | MGI:99440 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 12489 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable protein phosphatase binding activity and sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to be located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. Predicted to be active in plasma membrane. Is expressed in central nervous system; genitourinary system; spleen; and submandibular gland. Orthologous to several human genes including CD33 (CD33 molecule). PHENOTYPE: Mice homozygous for disruptions in this gene show slight reductions in mean erythrocyte count and hematocrit and increased concentration of blood aspartate aminotransaminase. There is also a hyporesponsiveness to induced peritonitis and a weaker IL-6 response to LPS-induced systemic inflammation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
