| Primary Identifier | MGI:108086 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 433759 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables several functions, including E-box binding activity; Krueppel-associated box domain binding activity; and histone modifying activity. Involved in several processes, including eyelid development in camera-type eye; fungiform papilla formation; and regulation of gene expression. Acts upstream of or within several processes, including negative regulation of signal transduction; nervous system development; and positive regulation of oligodendrocyte differentiation. Located in neuronal cell body and nucleus. Part of NuRD complex; heterochromatin; and transcription repressor complex. Is expressed in several structures, including brain; early conceptus; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human HDAC1 (histone deacetylase 1). PHENOTYPE: Mice homozygous for disruptions in this gene die as embryos between E9.5 and E10.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
