Primary Identifier | MGI:1098551 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 12750 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables protein serine/threonine kinase activity and protein tyrosine kinase activity. Predicted to be involved in regulation of RNA splicing. Located in nucleus. Is expressed in several structures, including endocrine gland; gonad; hemolymphoid system gland; liver; and tongue. Orthologous to human CLK4 (CDC like kinase 4). PHENOTYPE: Mice homozygous for a conditional allele activated in cardiomyocytes exhibit congestive heart failure, enlarged hearts and lungs, cardiac interstitial fibrosis, and abnormal cardiomyocyte sarcomere morphology. [provided by MGI curators] |