Primary Identifier | MGI:5910803 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Rhot1 |
Transmission | Germline | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
description | The ES cell used to generate this allele was derived from a C57BL/6 mouse whereas that used to generate the tm1Jmsu allele was from a segregating B6;129 background. The same construct was used in both targeted alleles. |
molecularNote | A loxP site, FRT-flanked neomycin resistance gene, exon 2, and a loxP site replaced exon 2. The FRT-flanked neomycin resistance gene was removed via Flp-mediated recombination leaving exon 2 flanked by loxP sites. |