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Allele : Ptpn11<tm2Bgn> protein tyrosine phosphatase, non-receptor type 11; targeted mutation 2, Benjamin G Neel

Primary Identifier  MGI:3621004 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptpn11
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing a splice acceptor, Beta-gal, and pgk-neo replaced exon 2 of the locus by homologous recombination. Western blot demonstrated that mutant mice expressed only a truncated protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Shp2 Ex2<->,
  • Shp2 Ex2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele