| Primary Identifier | MGI:1920328 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 73078 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable metalloendopeptidase activity. Predicted to contribute to metallopeptidase activity. Predicted to be involved in protein processing involved in protein targeting to mitochondrion. Predicted to act upstream of or within proteolysis. Located in mitochondrial inner membrane. Is expressed in several structures, including extraembryonic component; gallbladder; genitourinary system; gut gland; and nervous system. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 6. Orthologous to human PMPCB (peptidase, mitochondrial processing subunit beta). PHENOTYPE: Mice homozygous for a knock-out allele show normal blastocyst formation but exhibit complete embryonic lethality between implantation and somite formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
