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Protein Domain : Ubiquitin carboxyl-terminal hydrolase L1

Primary Identifier  IPR030297 Type  Family
Short Name  UCHL1
description  Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is a deubiquitinase that has dual hydrolase and ligase activities []. It is the most abundant protein in brain lysates (1-2%), regulating the timing and the pattern of ubiquitination []. Mutations in the UCHL1 gene has been linked to neurodegenerative diseases [, ]. UCHL1 also pays a major role in oncogenesis [].

0 Child Features

0 Parent Features

3 Protein Domain Regions