|  Help  |  About  |  Contact Us

Protein Coding Gene : Abcc3 ATP-binding cassette, sub-family C member 3

Primary Identifier  MGI:1923658 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  76408
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable ABC-type transporter activity; glucuronoside transmembrane transporter activity; and icosanoid transmembrane transporter activity. Predicted to be involved in carboxylic acid transport; monoatomic anion transmembrane transport; and xenobiotic transmembrane transport. Predicted to act upstream of or within canalicular bile acid transport. Located in basolateral plasma membrane. Is expressed in alimentary system; embryo; liver; and small intestine. Orthologous to human ABCC3 (ATP binding cassette subfamily C member 3).
PHENOTYPE: Mice homozygous for disruptions in this gene exhibit increased liver bile acid levels after bile duct ligation [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1700019L09 gene,
  • ATP-binding cassette, sub-family C member 3,
  • Abcc3,
  • MRP3,
  • 1700019L09Rik

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

10 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For