| First Author | Vyleta NP | Year | 2023 |
| Journal | Commun Biol | Volume | 6 |
| Issue | 1 | Pages | 290 |
| PubMed ID | 36934174 | Mgi Jnum | J:334968 |
| Mgi Id | MGI:7447562 | Doi | 10.1038/s42003-023-04678-5 |
| Citation | Vyleta NP, et al. (2023) Enhanced excitability but mature action potential waveforms at mossy fiber terminals of young, adult-born hippocampal neurons in mice. Commun Biol 6(1):290 |
| abstractText | Adult-born granule neurons pass through immature critical periods where they display enhanced somatic excitability and afferent plasticity, which is believed to endow them with unique roles in hippocampal learning and memory. Using patch clamp recordings in mouse hippocampal slices, here we show that young neuron hyper-excitability is also observed at presynaptic mossy fiber terminals onto CA3 pyramidal neurons. However, action potential waveforms mature faster in the bouton than in the soma, suggesting rapid efferent functionality during immature stages. |
