| Primary Identifier | MGI:3056939 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Igh-6/Igh-V281)3Jwt |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The construct for Tg(Igh-6/Igh-V281)3Jwt has a germ line reversion encoding D at residue 49 (from G)and another encoding V (from E) at residue 56. The transgene encodes an IgMa constant region with a variable region nearly identical to that of the BALB/c IgG1 mouse anti-human insulin monoclonal antibody, mAb125, (from the American Type Culture Collection) but lacking the high affinity specificity for insulin. |
