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Protein Coding Gene : Pilra paired immunoglobin-like type 2 receptor alpha

Primary Identifier  MGI:2450529 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  231805
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable MHC class I protein binding activity. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Is expressed in heart ventricle; lung; and urethra. Orthologous to several human genes including PILRA (paired immunoglobin like type 2 receptor alpha).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased increased alanine transferase, blood urea nitrogen, lactate dehydrogenase, neutrophils and mortality and altered liver morphology (massive hemorrhage, disorganized hepatic cords and karyolysis of hepatocytes) following treatment with LPS. [provided by MGI curators]
  • synonyms:
  • Pilra,
  • expressed sequence AV021745,
  • AV021745,
  • paired immunoglobin-like type 2 receptor alpha,
  • FDF03,
  • MGI:2141104

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For