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Protein Coding Gene : Scn7a sodium channel, voltage-gated, type VII, alpha

Primary Identifier  MGI:102965 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  20272
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables sodium channel activity. Involved in osmosensory signaling pathway. Acts upstream of or within cellular homeostasis; response to bacterium; and sodium ion homeostasis. Located in glial cell projection. Is active in plasma membrane. Is expressed in heart and heart ventricle. Orthologous to human SCN7A (sodium voltage-gated channel alpha subunit 7).
PHENOTYPE: Mice homozygous for disruptions in this gene have a modified dietary preference for NaCl but are phenotypically normal otherwise. [provided by MGI curators]
  • synonyms:
  • Scn7a,
  • Nax,
  • NaG,
  • Nav2,
  • 1110034K09Rik,
  • MGI:2139022,
  • RIKEN cDNA 1110034K09 gene,
  • Scn6a,
  • expressed sequence AI642000,
  • AI642000,
  • sodium channel, voltage-gated, type VII, alpha,
  • Nav2.3,
  • MGD-MRK-23802,
  • MGI:1915995,
  • MGD-MRK-14325,
  • MGI:98252

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Genome

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1 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

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