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Protein Coding Gene : Txndc5 thioredoxin domain containing 5

Primary Identifier  MGI:2145316 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  105245
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables protein disulfide isomerase activity and protein-disulfide reductase activity. Predicted to be involved in protein folding. Located in endoplasmic reticulum lumen. Is expressed in several structures, including brain; eye; immune system; intestine; and male reproductive gland or organ. Orthologous to human TXNDC5 (thioredoxin domain containing 5).
PHENOTYPE: Mcie homozygous for a null allele exhibit protection from isoproterenol-induced cardiac fibrosis and myocardial dysfunction. [provided by MGI curators]
  • synonyms:
  • AL022641,
  • PC-TRP,
  • thioredoxin domain containing 5,
  • Txndc5,
  • expressed sequence AL022641,
  • ERp46

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For