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Publication : Cloning and expression of a mouse cDNA encoding p59, an immunophilin that associates with the glucocorticoid receptor.

First Author  Schmitt J Year  1993
Journal  Gene Volume  132
Issue  2 Pages  267-71
PubMed ID  7693550 Mgi Jnum  J:15654
Mgi Id  MGI:63771 Doi  10.1016/0378-1119(93)90206-i
Citation  Schmitt J, et al. (1993) Cloning and expression of a mouse cDNA encoding p59, an immunophilin that associates with the glucocorticoid receptor. Gene 132(2):267-71
abstractText  A cDNA encoding the homologue of the rabbit immunophilin p59 was cloned from a mouse NIH-3T3 cell line library. Antibodies were generated against the N-terminal fragment of the protein produced in bacteria. Western blotting experiments suggest that homologous proteins are present in several other cell lines tested. Production of mouse p59 using recombinant vaccinia viruses resulted in a protein with the expected size of 59 kDa that can interact with the recombinant glucocorticoid receptor, as shown by co-immunoprecipitation experiments.
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