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Protein Coding Gene : Bmp8a bone morphogenetic protein 8a

Primary Identifier  MGI:104515 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  12163
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable cytokine activity. Involved in osteoblast differentiation. Acts upstream of or within germ cell development and spermatogenesis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and musculoskeletal system. Orthologous to several human genes including BMP8A (bone morphogenetic protein 8a).
PHENOTYPE: About half of the males homozygous for targeted mutations of this gene show spermatogenesis defects and germ cell degeneration. [provided by MGI curators]
  • synonyms:
  • Bmp8a,
  • osteogenic protein 2,
  • MGD-MRK-18614,
  • OP2,
  • MGD-MRK-25946,
  • bone morphogenetic protein 8a,
  • Bmp7r1,
  • bone morphogenetic protein 7, related 1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For