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Protein Coding Gene : Mms22l MMS22-like, DNA repair protein

Primary Identifier  MGI:2684980 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  212377
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination; protein localization to chromatin; and replication fork processing. Predicted to act upstream of or within DNA repair and chromatin organization. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of FACT complex and MCM complex. Predicted to be active in nuclear replication fork and site of double-strand break. Is expressed in cerebral cortex ventricular layer. Orthologous to human MMS22L (MMS22 like, DNA repair protein).
PHENOTYPE: Mice homozygous for a null mutation die prenatally. Heterozygous mice exhibit defects in pinna responses. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA F730047E07 gene,
  • MMS22-like, DNA repair protein,
  • F730047E07Rik,
  • Mms22l,
  • Gm134,
  • gene model 134, (NCBI)

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