| First Author | Thien H | Year | 1996 |
| Journal | Biochim Biophys Acta | Volume | 1307 |
| Issue | 3 | Pages | 267-9 |
| PubMed ID | 8688459 | Mgi Jnum | J:34147 |
| Mgi Id | MGI:81616 | Doi | 10.1016/0167-4781(96)00079-6 |
| Citation | Thien H, et al. (1996) Cloning and sequence analysis of the murine Gli3 cDNA. Biochim Biophys Acta 1307(3):267-9 |
| abstractText | The zinc finger gene Gli3 plays a role in limb and brain development. To facilitate the molecular analysis of different mouse mutations of this gene, the murine cDNA was isolated and sequenced. This 5113 bp cDNA encodes a putative protein of 1596 amino acids. Comparison of the murine and human GLI3 cDNA revealed an overall homology of 85% between the deduced amino acid sequences. More importantly, several regions of the protein, including the zinc fingers, are more highly conserved ( > 95%), suggesting that these represent functional domains in the Gli3 protein. |
