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Protein Coding Gene : Tcp1 t-complex protein 1

Primary Identifier  MGI:98535 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  21454
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable protein folding chaperone; ubiquitin protein ligase binding activity; and unfolded protein binding activity. Acts upstream of or within binding activity of sperm to zona pellucida. Located in several cellular components, including acrosomal vesicle; cell body; and pericentriolar material. Part of chaperonin-containing T-complex; heterochromatin; and zona pellucida receptor complex. Is expressed in several structures, including cerebral cortex; extraembryonic component; genitourinary system; humerus; and immune system. Orthologous to human TCP1 (t-complex 1).
PHENOTYPE: There are two electrophoretic alleles known; allele a occurs in all complete t haplotype chromosomes and allele b in wild-type strains. There are multiple changes between the amino acid sequences of the TCP1A and TCP1B proteins encoded by the two alleles. [provided by MGI curators]
  • synonyms:
  • AI528772,
  • MGD-MRK-36524,
  • MGD-MRK-14810,
  • MGI:2146890,
  • p63,
  • MGD-MRK-13116,
  • MGI:107944,
  • TRic,
  • c-cpn,
  • MGD-MRK-14826,
  • CCT,
  • T-protein 63,
  • expressed sequence AI528772,
  • p63/6.9 protein,
  • Tcp-1,
  • MGD-MRK-15176,
  • chaperonin subunit 1 (alpha),
  • Tcp1,
  • Tp63,
  • t-complex protein 1,
  • Ccta,
  • Cct1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For