| Primary Identifier | IPR028143 | Type | Family |
| Short Name | Get2/sif1 |
| description | This entry represents the GET complex subunit Get2 and its homologue, sif1 from Schizosaccharomyces pombe. The Golgi to ER traffic (GET) complex is composed of Get1, Get2 and Get3. The complex is involved in the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum []. Get1 and Get2 form a transmembrane complex and interact with Get3, an ATPase which recognises and selectively binds the transmembrane domain of TA proteins in the cytosol [, ]. In Schizosaccharomyces pombe, sif1 interacts with Kms1 and Sad1, which are constitutive membrane-bound components of the SPB (spindle pole body) that interact with each other []. |
