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Protein Domain : Serine/threonine-protein kinase Kin4/ppk1, catalytic domain

Primary Identifier  IPR034674 Type  Domain
Short Name  STK_Kin4/ppk1
description  Saccharomyces cerevisiae Kin4 is a central component of the spindle position checkpoint (SPOC), which monitors spindle position and regulates the mitotic exit network (MEN) [, ]. Kin4 associates with spindle pole bodies in mother cells to inhibit MEN signaling and delay mitosis until the anaphase nucleus is properly positioned along the mother-bud axis. Kin4 activity is regulated by both the bud neck-associated kinase Elm1 and protein phosphatase 2A [, ].The fission yeast homologue is known as ppk1 [].

0 Child Features

1 Parent Features

0 Protein Domain Regions