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Allele : Gt(ROSA)26Sor<tm1.1(CAG-CHRM3*/mCherry)Stak> gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Takeshi Sakurai
Primary Identifier  MGI:6724031 Allele Type  Targeted
Attribute String  Conditional ready, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct consisting of a CAG promoter, a loxp, 2xpA, FRT-flanked Pgk-neo selection cassette, STOP cassette, loxp, followed by a hM3Dq/mCherry fusion protein, pA signal all inserted into the Gt(ROSA)26Sor locus was used to generate the mouse line by homologous recombination in the C57BL/6N ES cells. The pgk-Neo cassette was removed with FLP66. CAG promoter drives expression of hM3Dq-mCherry only after Cre-mediated excision of the floxed stopper element.
  • mutations:
  • Insertion
  • synonyms:
  • Rosa26<dreaddm3>,
  • Rosa26<dreaddm3>
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1 Feature

Trail: Allele

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